Détails des nouvelles

À la maison > Nouvelles >

Actualités de l'entreprise Layout and Design of Cleanrooms Across Different Industries

Événements

Nouvelles

Les affaires

Nous Contacter

Mr. Jack

chenjinglin@gd-hao.com

86-757-86689889

Contactez-nous maintenant

Layout and Design of Cleanrooms Across Different Industries

2025-09-02

I. General Design Principles

Functional Zoning

Cleanrooms must be divided into clean zones, semi-clean zones, and auxiliary areas. Functional zones should be independent and physically isolated.
Process flows must follow unidirectional principles to avoid cross-contamination between personnel and materials.
Core clean areas should be located at the center or upwind side of the building to minimize external interference.

Airflow Organization

Unidirectional Flow Cleanrooms: Use vertical laminar flow or horizontal laminar flow with an airflow velocity of 0.3–0.5 m/s. Suitable for high-cleanliness scenarios such as semiconductors and biopharmaceuticals.
Non-Unidirectional Flow Cleanrooms: Maintain cleanliness through high-efficiency filtration and dilution, with air change rates of 15–60 times per hour. Suitable for medium-to-low cleanliness scenarios such as food and cosmetics.
Mixed Flow Cleanrooms: Combine unidirectional flow in core areas with non-unidirectional flow in peripheral areas to balance cost and efficiency.

Pressure Differential Control

The pressure difference between clean and non-clean areas should be ≥5 Pa, and between clean areas and the outdoors ≥10 Pa.
Adjacent clean areas should have a reasonable pressure gradient, with higher-pressure zones in higher-cleanliness areas.

II. Industry-Specific Design Requirements

(1) Semiconductor Industry Cleanrooms

Cleanliness Class

Core process areas (e.g., photolithography, etching) must meet ISO 14644-1 Class 1 or Class 10, with particle concentrations ≤3,520 particles/m³ (0.5 μm).
Auxiliary areas may have relaxed cleanliness standards of ISO Class 7 or 8.

Temperature and Humidity Control

Temperature: 22 ± 1°C, relative humidity: 40%–60%, maintained by constant temperature and humidity HVAC systems.

Anti-Static Design

Conductive epoxy flooring or anti-static PVC flooring with resistance ≤1 × 10⁶ Ω.
Personnel must wear anti-static clothing and shoe covers; equipment grounding resistance ≤1 Ω.

Layout Example

Core process areas are located at the building center, surrounded by equipment and testing rooms.
Materials enter through airlocks; personnel enter through air showers.
Exhaust systems are independent, with emissions filtered through HEPA before release.

(2) Biopharmaceutical Industry Cleanrooms

Cleanliness Class

Aseptic filling areas must meet Grade A (ISO Class 5), with localized Class 100 conditions.
Cell culture and bacterial operation areas must meet Grade B (ISO Class 6).
Auxiliary areas (e.g., sterilization rooms, material storage) must meet Grade C (ISO Class 7) or Grade D (ISO Class 8).

Biosafety Requirements

Experiments involving highly pathogenic microorganisms must be conducted in BSL-2 or BSL-3 laboratories with negative pressure, interlocked doors, and emergency shower equipment.
Sterilization rooms must use fire-resistant, high-temperature-resistant materials and be equipped with steam sterilizers or hydrogen peroxide vaporizers.

Layout Example

Bacterial and cell culture rooms are isolated and physically separated from clean filling areas.
Materials enter via pass-through windows; personnel enter through changing rooms and buffer zones.
Exhaust systems are equipped with HEPA filters and activated carbon adsorption units.

(3) Food Industry Cleanrooms

Cleanliness Class

Ready-to-eat food packaging areas must meet Class 100,000 (ISO Class 8), with particle concentrations ≤3.52 million/m³ (0.5 μm).
Raw material handling and non-ready-to-eat food packaging areas must meet Class 300,000 (ISO Class 9).

Temperature and Humidity Control

Temperature: 18–26°C, relative humidity ≤75% to prevent microbial growth from condensation.

Layout Example

Clean operation areas (e.g., inner packaging) are located upwind; semi-clean areas (e.g., raw material handling) are downwind.
Materials enter through buffer rooms; personnel enter through changing rooms and hand-sanitizing areas.
Exhaust systems use primary and medium-efficiency filters, with regular filter replacements.

(4) Cosmetics Industry Cleanrooms

Cleanliness Class

Emulsification and filling rooms must meet Class 100,000 (ISO Class 8).
Raw material storage and packaging areas must meet Class 300,000 (ISO Class 9).

Material Selection

Walls use mildew-resistant paint or color steel plates; floors use epoxy self-leveling coatings with sealed seams.
Lighting fixtures use sealed cleanroom lamps to prevent dust accumulation.

Layout Example

Emulsification and filling rooms are isolated and equipped with localized Class 100 clean benches.
Materials enter via pass-through windows; personnel enter through changing rooms and air showers.
Exhaust systems use activated carbon adsorption to remove volatile organic compounds.

IV. Safety and Emergency Design

Emergency Evacuation

Each cleanroom level must have ≥2 emergency exits; evacuation doors open in the direction of escape.
Air showers must have bypass doors if occupancy exceeds 5 people.

Fire Protection Facilities

Clean areas use gas fire suppression systems (e.g., heptafluoropropane) to avoid water damage.
Emergency lighting and evacuation signs must provide ≥30 minutes of backup power.

Emergency Response

Biosafety laboratories must have emergency evacuation routes and eyewash stations.
Chemical storage areas must have spill containment trays and absorbent materials.

Détails des nouvelles

À la maison > Nouvelles >

Actualités de l'entreprise-Layout and Design of Cleanrooms Across Different Industries

Événements

Nouvelles

Les affaires

Layout and Design of Cleanrooms Across Different Industries

2025-09-02

I. General Design Principles

Functional Zoning

Cleanrooms must be divided into clean zones, semi-clean zones, and auxiliary areas. Functional zones should be independent and physically isolated.
Process flows must follow unidirectional principles to avoid cross-contamination between personnel and materials.
Core clean areas should be located at the center or upwind side of the building to minimize external interference.

Airflow Organization

Unidirectional Flow Cleanrooms: Use vertical laminar flow or horizontal laminar flow with an airflow velocity of 0.3–0.5 m/s. Suitable for high-cleanliness scenarios such as semiconductors and biopharmaceuticals.
Non-Unidirectional Flow Cleanrooms: Maintain cleanliness through high-efficiency filtration and dilution, with air change rates of 15–60 times per hour. Suitable for medium-to-low cleanliness scenarios such as food and cosmetics.
Mixed Flow Cleanrooms: Combine unidirectional flow in core areas with non-unidirectional flow in peripheral areas to balance cost and efficiency.

Pressure Differential Control

The pressure difference between clean and non-clean areas should be ≥5 Pa, and between clean areas and the outdoors ≥10 Pa.
Adjacent clean areas should have a reasonable pressure gradient, with higher-pressure zones in higher-cleanliness areas.

II. Industry-Specific Design Requirements

(1) Semiconductor Industry Cleanrooms

Cleanliness Class

Core process areas (e.g., photolithography, etching) must meet ISO 14644-1 Class 1 or Class 10, with particle concentrations ≤3,520 particles/m³ (0.5 μm).
Auxiliary areas may have relaxed cleanliness standards of ISO Class 7 or 8.

Temperature and Humidity Control

Temperature: 22 ± 1°C, relative humidity: 40%–60%, maintained by constant temperature and humidity HVAC systems.

Anti-Static Design

Conductive epoxy flooring or anti-static PVC flooring with resistance ≤1 × 10⁶ Ω.
Personnel must wear anti-static clothing and shoe covers; equipment grounding resistance ≤1 Ω.

Layout Example

Core process areas are located at the building center, surrounded by equipment and testing rooms.
Materials enter through airlocks; personnel enter through air showers.
Exhaust systems are independent, with emissions filtered through HEPA before release.

(2) Biopharmaceutical Industry Cleanrooms

Cleanliness Class

Aseptic filling areas must meet Grade A (ISO Class 5), with localized Class 100 conditions.
Cell culture and bacterial operation areas must meet Grade B (ISO Class 6).
Auxiliary areas (e.g., sterilization rooms, material storage) must meet Grade C (ISO Class 7) or Grade D (ISO Class 8).

Biosafety Requirements

Experiments involving highly pathogenic microorganisms must be conducted in BSL-2 or BSL-3 laboratories with negative pressure, interlocked doors, and emergency shower equipment.
Sterilization rooms must use fire-resistant, high-temperature-resistant materials and be equipped with steam sterilizers or hydrogen peroxide vaporizers.

Layout Example

Bacterial and cell culture rooms are isolated and physically separated from clean filling areas.
Materials enter via pass-through windows; personnel enter through changing rooms and buffer zones.
Exhaust systems are equipped with HEPA filters and activated carbon adsorption units.

(3) Food Industry Cleanrooms

Cleanliness Class

Ready-to-eat food packaging areas must meet Class 100,000 (ISO Class 8), with particle concentrations ≤3.52 million/m³ (0.5 μm).
Raw material handling and non-ready-to-eat food packaging areas must meet Class 300,000 (ISO Class 9).

Temperature and Humidity Control

Temperature: 18–26°C, relative humidity ≤75% to prevent microbial growth from condensation.

Layout Example

Clean operation areas (e.g., inner packaging) are located upwind; semi-clean areas (e.g., raw material handling) are downwind.
Materials enter through buffer rooms; personnel enter through changing rooms and hand-sanitizing areas.
Exhaust systems use primary and medium-efficiency filters, with regular filter replacements.

(4) Cosmetics Industry Cleanrooms

Cleanliness Class

Emulsification and filling rooms must meet Class 100,000 (ISO Class 8).
Raw material storage and packaging areas must meet Class 300,000 (ISO Class 9).

Material Selection

Walls use mildew-resistant paint or color steel plates; floors use epoxy self-leveling coatings with sealed seams.
Lighting fixtures use sealed cleanroom lamps to prevent dust accumulation.

Layout Example

Emulsification and filling rooms are isolated and equipped with localized Class 100 clean benches.
Materials enter via pass-through windows; personnel enter through changing rooms and air showers.
Exhaust systems use activated carbon adsorption to remove volatile organic compounds.

IV. Safety and Emergency Design

Emergency Evacuation

Each cleanroom level must have ≥2 emergency exits; evacuation doors open in the direction of escape.
Air showers must have bypass doors if occupancy exceeds 5 people.

Fire Protection Facilities

Clean areas use gas fire suppression systems (e.g., heptafluoropropane) to avoid water damage.
Emergency lighting and evacuation signs must provide ≥30 minutes of backup power.

Emergency Response

Biosafety laboratories must have emergency evacuation routes and eyewash stations.
Chemical storage areas must have spill containment trays and absorbent materials.

Panneau sandwich de salle blanche fabriqué à la machine

Panneau sandwich de salle blanche fait à la main

Porte pivotante de salle blanche

Porte coulissante automatique de salle blanche

fenêtre de cleanroom

Profil en aluminium de salle blanche

Planchers en PVC en salle blanche

Boîte de passage de Cleanroom

Douche d'air de Cleanroom

Boîte à filtres HEPA de salle blanche

Unité de filtrage de fan de FFU

Filtre à air de Cleanroom

Porte à volets à roulement rapide

Équipements de Cleanroom

Panneau sandwich de salle blanche fabriqué à la machine

Panneau sandwich de salle blanche fait à la main

Porte pivotante de salle blanche

Porte coulissante automatique de salle blanche

fenêtre de cleanroom

Profil en aluminium de salle blanche

Planchers en PVC en salle blanche

Boîte de passage de Cleanroom

Douche d'air de Cleanroom

Boîte à filtres HEPA de salle blanche

Unité de filtrage de fan de FFU

Filtre à air de Cleanroom

Porte à volets à roulement rapide

Équipements de Cleanroom

Détails des nouvelles

Actualités de l'entreprise Layout and Design of Cleanrooms Across Different Industries

Nouvelles

Les affaires

Layout and Design of Cleanrooms Across Different Industries

Actualités de l'entreprise-Layout and Design of Cleanrooms Across Different Industries

Nouvelles

Les affaires

Layout and Design of Cleanrooms Across Different Industries